Through long term supplementation, increases in Nerve Growth Factor have been shown in studies.
NGF is a protein that is involved with the generation of new neurons meaning potential long-term benefits to memory
.Noopept has been shown to acutely increase memory recall, which can explain my improvement in verbal fluency;
I can quickly remember the right words at the right time to express my thoughts.Improves Short Term FocusIncreases BDNF, which stands for brain-derived-neurotrophic factor, which works similarly to NGF in helping support existing neurons, and encourages the growth of new ones.
Increases feelings of wakefulnessPotentiates other nootropics
How does it work? Noopept has 4 distinct mechanisms of action:
In vitro studies of Noopept have shown signs that it operates on an antioxidative mechanism of action which protects neurons from apoptosis, which is cell death. In English: protects brain cells from dying. [S]Noopept works through the inhibition of glutamate neurotoxicityNoopept works to increase neuronal plasticity. Neuronal plasticity or neuroplasticity is an umbrella term that refers to the brains ability to change throughout a human’s life. By increasing this malleability, noopept provides the brain to respond positively to the stimuli we provide, aka, learn and focus better.Noopept works to increase expression of phenylacetic acid, proplyglycine, and cyclo-prolyglycine in the brain, which are endogenous Nootropics, or cognitive enhancers. [S]
Dose it at 10 – 30 mg/day, according to most sources (30 mg is what I traditionally used), and you will feel sharper, slightly more alert, your sensory perception enhanced a bit, and your verbal fluency unmatched. [S]
Many users, including myself suggest that Noopept works very well with Aniracetam, a mild nootropic in the ampakine family that has many anxiolytic effects. Noopept as a standalone is stimulatory and slightly anxiolytic. With aniracetam, verbal fluency and feelings of sociability are greatly increased, and from my experience along with those of others, it seems like the two compounds potentiate each other. I usually try to get a choline source, whether it is alpha-GPC in supplemental form, or a whole lot of eggs whites in the morning. Regardless on whether you stack noopept with other potentiating compounds, or take it on it's own, it would be in your favor as a the high-impact individual that you are to give it a try.